Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378833 | 0.90 | TSHR (0.71) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL4302217 | 0.89 | TSHR (0.50) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL4301097 | 0.89 | TSHR (0.50) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL26788164 | 0.88 | ACHE (0.59) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL21447698 | 0.87 | LOXL2 (0.52) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL4314778 | 0.85 | TDP1 (0.46) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL11367135 | 0.85 | TSHR (0.48) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL22352447 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL23170656 | 0.83 | LOXL2 (0.48) | ALDH1A1CYP3A4TSHRTDP1GFER | |
| SCHEMBL23314261 | 0.82 | CYP19A1 (0.62) | CYP3A4TSHRLOXL2MAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2024-01-04 | — | — | US | claimed |
| EP-4079316-A1 | PROCOAGULANT COMPOUNDS | Bioverativ Therapeutics Inc. (US) | 2022-10-26 | — | — | EP | claimed |
| US-20220257789-A1 | ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS | EXELIXIS, INC. | 2022-08-18 | — | — | US | claimed |
| US-20220243189-A1 | PROCOAGULANT COMPOUNDS | BIOGEN MA INC. | 2022-08-04 | — | — | US | claimed |
| EP-3994150-A1 | ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS | Iconic Therapeutics, Inc. (US) | 2022-05-11 | — | — | EP | claimed |
| US-20220098191-A1 | G-A CROSSLINKING CYTOTOXIC AGENTS | Pheon Therapeutics Ltd. (GB) | 2022-03-31 | — | — | US | claimed |
| CN-114222752-A | Anti-tissue factor antibody-drug conjugates and related methods | 伊科尼克治疗公司 | 2022-03-22 | — | — | CN | claimed |
| EP-3693000-B1 | PROCOAGULANT COMPOUNDS | BIOVERATIV THERAPEUTICS INC (US) | 2022-03-02 | — | — | EP | claimed |
| EP-3917924-A1 | G-A CROSSLINKING CYTOTOXIC AGENTS | Femtogenix Limited (GB) | 2021-12-08 | — | — | EP | claimed |
| CN-113024388-A | Preparation method of p-anisidine | 宁夏华御化工有限公司 | 2021-06-25 | — | — | CN | claimed |
| EP-3693000-A1 | PROCOAGULANT COMPOUNDS | Bioverativ Therapeutics Inc. (US) | 2020-08-12 | — | — | EP | claimed |
| WO-2020157491-A1 | G-A CROSSLINKING CYTOTOXIC AGENTS | FEMTOGENIX LIMITED (GB) | 2020-08-06 | — | — | WO | claimed |
| US-20190309280-A1 | PROCOAGULANT COMPOUNDS | BIOGEN MA INC. | 2019-10-10 | — | — | US | claimed |
| US-20190144443-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2019-05-16 | — | — | US | claimed |
| EP-3455225-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | Femtogenix Limited (GB) | 2019-03-20 | — | — | EP | claimed |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2017-12-14 | — | — | US | claimed |
| WO-2017194960-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | FEMTOGENIX LIMITED (GB) | 2017-11-16 | — | — | WO | claimed |
| US-20150184142-A1 | PROCOAGULANT COMPOUNDS | BIOGEN IDEC MA INC. (US) | 2015-07-02 | — | — | US | claimed |
| EP-2858659-A1 | PROCOAGULANT COMPOUNDS | Biogen Idec MA Inc. (US) | 2015-04-15 | — | — | EP | claimed |
| WO-2013185113-A1 | PROCOAGULANT COMPOUNDS | BIOGEN IDEC MA INC. (US) | 2013-12-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098191-A1 | G-A CROSSLINKING CYTOTOXIC AGENTS | CCNA1, GNA15, RPS26 | ALDH1A1 1830/4885CYP3A4 3363/4885TSHR 1326/4885 |
| US-20220243189-A1 | PROCOAGULANT COMPOUNDS | PLG, F2, PLAT | ALDH1A1 4124/4885CYP3A4 1524/4885TSHR 1567/4885 |
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | TUBA1C, MTX2, CCNO | ALDH1A1 2285/4885CYP3A4 3810/4885TSHR 395/4885 |
| US-20220257789-A1 | ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS | F3, F13B, TFPI | ALDH1A1 1620/4885CYP3A4 3400/4885TSHR 480/4885 |
| US-20150184142-A1 | PROCOAGULANT COMPOUNDS | PLG, F2, PLAT | ALDH1A1 4124/4885CYP3A4 1524/4885TSHR 1567/4885 |
| US-20190144443-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | TUBA1C, MTX2, CCNO | ALDH1A1 2302/4885CYP3A4 3811/4885TSHR 404/4885 |
| US-20190309280-A1 | PROCOAGULANT COMPOUNDS | PLG, F2, FGB | ALDH1A1 3705/4885CYP3A4 1831/4885TSHR 1961/4885 |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | CD2BP2, CACYBP, CALCOCO2 | ALDH1A1 4588/4885CYP3A4 4803/4885TSHR 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.