Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282614 | 0.88 | PIN1 (0.46) | PIN1PREPFAPPEPDPIK3CD | |
| SCHEMBL17282586 | 0.88 | PIN1 (0.46) | PIN1PREPFAPPEPDPIK3CD | |
| SCHEMBL17282582 | 0.84 | PIN1 (0.63) | PIN1PREPFAPPEPDPIK3CD | |
| SCHEMBL8203665 | 0.79 | ATM (0.48) | PIN1PEPDMMP2ANPEPATM | |
| SCHEMBL17282580 | 0.77 | PREP (0.52) | PIN1PREPFAPMBOAT4DPP4 | |
| SCHEMBL15110042 | 0.75 | ATM (0.63) | PREPFAPPIK3CDATMDPP4 | |
| SCHEMBL16267210 | 0.75 | ATM (0.63) | PREPFAPPIK3CDATMDPP4 | |
| SCHEMBL15110041 | 0.75 | ATM (0.63) | PREPFAPPIK3CDATMDPP4 | |
| SCHEMBL23314580 | 0.75 | PREP (0.61) | PREPFAPPEPDDPP4DPP8 | |
| SCHEMBL16267049 | 0.75 | ATM (0.63) | PREPFAPPIK3CDATMDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |