Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354292 | 0.82 | GAA (0.54) | RECQLCA14HDAC6HDAC1HDAC2 | |
| SCHEMBL755177 | 0.80 | CA14 (0.35) | RECQLCA14BUB1HDAC6HDAC1 | |
| SCHEMBL15285839 | 0.78 | CTSD (0.39) | CA14BUB1HDAC6HDAC1HDAC2 | |
| SCHEMBL381146 | 0.77 | HDAC6 (0.39) | CA14BUB1HDAC6HDAC1HDAC2 | |
| SCHEMBL19493237 | 0.77 | MAOA (0.40) | CA14HDAC6HDAC1HDAC2FPR3 | |
| SCHEMBL23616307 | 0.76 | DNM1 (0.43) | CA14HDAC6HDAC1HDAC2 | |
| Succinic Acid SCHEMBL28315096 | 0.75 | PHF8 (0.39) | CA14BUB1HDAC6HDAC1HDAC2 | |
| SCHEMBL1105464 | 0.75 | HDAC6 (0.34) | CA14BUB1HDAC6HDAC1HDAC2 | |
| SCHEMBL10260946 | 0.74 | HDAC6 (0.40) | CA14HDAC6HDAC1HDAC2FPR3 | |
| SCHEMBL31035920 | 0.74 | DNM1 (0.44) | CA14FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |