⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799458 | 0.70 | APLNR (0.31) | — | |
| SCHEMBL6548254 | 0.67 | — | — | |
| SCHEMBL18506404 | 0.64 | — | — | |
| SCHEMBL5986694 | 0.64 | — | — | |
| SCHEMBL4660383 | 0.63 | LMNA (0.42) | — | |
| SCHEMBL18710400 | 0.63 | LMNA (0.42) | — | |
| SCHEMBL21845314 | 0.63 | — | — | |
| SCHEMBL26984718 | 0.63 | — | — | |
| SCHEMBL14265651 | 0.63 | — | — | |
| SCHEMBL5477828 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |