SCHEMBL233153

SCHEMBL233153

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nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
CPB1 P15086 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.37
POLB P06746 3/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2C9 P11712 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.36
KDM4E B2RXH2 2/20 0.36
APOBEC3G Q9HC16 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.33
FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233154 1.00 TDP1 (0.40) TDP1CPB1SMN1; SMN2ALDH1A1POLB
SCHEMBL10724840 0.98 CPB1 (0.39) TDP1CPB1SMN1; SMN2ALDH1A1POLB
SCHEMBL20872375 0.80 TDP1 (0.43) TDP1CPB1SMN1; SMN2ALDH1A1POLB
SCHEMBL6894525 0.80 HTT (0.47) TDP1ALDH1A1POLB
SCHEMBL4457494 0.80 HTT (0.47) TDP1ALDH1A1POLB
SCHEMBL7887217 0.79 MGAM (0.38) TDP1ALDH1A1MEN1KMT2ATSHR
SCHEMBL7887219 0.79 MGAM (0.38) TDP1ALDH1A1MEN1KMT2ATSHR
SCHEMBL13931461 0.79 TSHR (0.37) ALDH1A1POLBMEN1KMT2ATSHR
SCHEMBL8936721 0.76 CPB1 (0.41) TDP1CPB1SMN1; SMN2ALDH1A1POLB
SCHEMBL17874 0.75 TDP1 (0.43) TDP1CPB1SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754039-B2 Targeted antimicrobial moieties C3 JIAN, INC. (US) 2014-06-17 US claimed
WO-2010078376-A2 FC-SPECIFIC POLYMER-CONJUGATED ANTIBODIES AND THEIR DIAGNOSTIC USE VENTANA MEDICAL SYSTEMS, INC. (US) 2010-07-08 WO claimed
US-4986980-A Water-soluble, carrier-bound paramagnetic metal containing diagnostic agents NYCOMED AS (NO) 1991-01-22 US claimed
WO-1989003041-A2 TRIDENTATE CONJUGATE AND METHOD OF USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1989-04-06 WO claimed
EP-4704604-A1 TASTE MODIFIERS COMPRISING A MAILLARD REACTION PRODUCT Givaudan SA (CH) 2026-03-11 EP disclosed
EP-4615958-A1 CELL COMPOSITIONS Givaudan SA (CH) 2025-09-17 EP disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
WO-2024227742-A1 TASTE MODIFIERS COMPRISING A MAILLARD REACTION PRODUCT GIVAUDAN SA (CH) 2024-11-07 WO disclosed
US-12049486-B2 PAC1 receptor agonists (MAXCAPs) and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-30 US disclosed
WO-2024100137-A1 CELL COMPOSITIONS GIVAUDAN SA (CH) 2024-05-16 WO disclosed
US-20230363427-A1 PREPARATION OF A SOLID FLAVOUR COMPOSITION, A COMPOSITION, FOOD COMPRISING THE COMPOSITION AND A FLAVOUR IMPARTING METHOD GIVAUDAN SA (CH) 2023-11-16 US disclosed
US-11707431-B2 Dental strips for the delivery of specifically targeted antimicrobial peptides C3 JIAN, LLC (US) 2023-07-25 US disclosed
US-4767745-A 1,5-DIFLUORO-2,4-DINITRO BENZENE AND 6-N-MALEIMIDOHEXANOIC ACID CHLORIDE AS COUPLING AGENTS; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS MERCK FROSST CANADA, INC. (CA) 1988-08-30 US disclosed
EP-0094777-B1 BIOLOGICALLY ACTIVE COMPOSITION AND IMMUNOASSAY USING THE SAME FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1987-03-18 EP disclosed
US-4621048-A Reagents containing an anti-ligand bound to an anti-enzyme and methods for employing said reagents in an immunoassy FUJIREBIO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
EP-0179959-A1 Conjugates of leukotrienes with proteins MERCK FROSST CANADA INC. (CA) 1986-05-07 EP disclosed
US-4582792-A COUPLING OF IMMOBILIZED ANTIGEN OR ANTIBODY WITH IMMOBILIZED ENZYME PRODUCT AND MEASUREMENT OF ACTIVITY FUJIREBIO KABUSHIKI KAISHA (JP) 1986-04-15 US disclosed
EP-0119767-A2 Method of measuring ligands FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1984-09-26 EP disclosed
EP-0094777-A1 Biologically active composition and immunoassay using the same FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1983-11-23 EP disclosed
US-4189505-A Pork-like flavorant and process for preparing same SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) 1980-02-19 US disclosed