Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 15/20 | 0.55 |
| ▸ | F2 | P00734 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20489830 | 0.89 | PRSS1 (0.58) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL18069355 | 0.87 | F10 (0.56) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL30005873 | 0.86 | F10 (0.59) | F10 | |
| SCHEMBL23316731 | 0.85 | NR1H4 (0.58) | — | |
| SCHEMBL8513394 | 0.84 | RECQL (0.59) | — | |
| SCHEMBL19910577 | 0.83 | ERCC1 (0.52) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24782509 | 0.81 | SLC7A5 (0.57) | F10 | |
| SCHEMBL30940553 | 0.80 | F10 (0.60) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL15373365 | 0.79 | PRSS1 (0.64) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL20487535 | 0.79 | NR1H4 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265445-B1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-05-05 | — | — | EP | disclosed |