Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 5/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 2/20 | 0.51 |
| ▸ | FNTB | P49356 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7327435 | 0.98 | NR1H4 (0.55) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4686379 | 0.92 | NR1H4 (0.52) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL30940553 | 0.89 | F10 (0.60) | MEP1BF10 | |
| SCHEMBL23316731 | 0.87 | NR1H4 (0.58) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL20486525 | 0.84 | FOLH1 (0.50) | MEP1BFOLH1RAB9ANPC1F10 | |
| Hydrochloric Acid SCHEMBL7324472 | 0.83 | USP28 (0.49) | FOLH1RAB9ANPC1F10CA1 | |
| SCHEMBL20302830 | 0.83 | LOXL2 (0.63) | RAB9AKMT2AF10MRGPRX4HIF1A | |
| SCHEMBL15600276 | 0.83 | NR1H4 (0.61) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL20489830 | 0.81 | PRSS1 (0.58) | F10 | |
| SCHEMBL13501302 | 0.80 | NR1H4 (0.76) | NR1H4MEP1BRAB9ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589631-B1 | IMIDAZO[4,5-C]RING COMPOUNDS CONTAINING GUANIDINE SUBSTITUTED BENZAMIDE GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2021-07-21 | — | — | EP | disclosed |
| US-10766896-B2 | Imidazo[4,5-c] ring compounds containing guanidine substituted benzamide groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-09-08 | — | — | US | disclosed |
| US-20200087298-A1 | Imidazo[4,5-c] Ring Compounds Containing Guanidine Substituted Benzamide Groups | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-03-19 | — | — | US | disclosed |
| WO-2018160552-A1 | IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING GUANIDINE SUBSTITUTED BENZAMIDE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087298-A1 | Imidazo[4,5-c] Ring Compounds Containing Guanidine Substituted Benzamide Groups | IL4, IFNG, IFNAR1 | NR1H4 1184/4885MEP1B 599/4885FOLH1 4034/4885 |
| US-10766896-B2 | Imidazo[4,5-c] ring compounds containing guanidine substituted benzamide groups | IL4, IFNG, IFNAR1 | NR1H4 1184/4885MEP1B 599/4885FOLH1 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.