Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 5/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316731 | 0.88 | NR1H4 (0.58) | RECQLMEP1B | |
| SCHEMBL15600277 | 0.88 | CYP1A2 (0.59) | F10KDM1AMAOAMAOBENPP2 | |
| SCHEMBL8513394 | 0.87 | RECQL (0.59) | RECQLCYP2C9CYP2C19 | |
| SCHEMBL30940553 | 0.86 | F10 (0.60) | F10KDM1AMAOAMAOBENPP2 | |
| SCHEMBL23316624 | 0.86 | PRSS1 (0.59) | F10 | |
| SCHEMBL2828029 | 0.86 | F10 (0.57) | F10KDM1AMAOAMAOBENPP2 | |
| SCHEMBL24782509 | 0.83 | SLC7A5 (0.57) | F10RECQLAURKARPS6KB1AURKB | |
| SCHEMBL13853740 | 0.83 | F10 (0.54) | F10KDM1AMAOAMAOBENPP2 | |
| SCHEMBL30491754 | 0.82 | F10 (0.56) | F10KDM1AMAOAMAOBENPP2 | |
| SCHEMBL14786544 | 0.82 | F10 (0.53) | F10KDM1AMAOAMAOBENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |