Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | MEP1B | Q16820 | 7/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005873 | 0.88 | F10 (0.59) | MEP1BRECQL | |
| SCHEMBL20487535 | 0.87 | NR1H4 (0.56) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL15600276 | 0.86 | NR1H4 (0.61) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7327435 | 0.85 | NR1H4 (0.55) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL8513394 | 0.85 | RECQL (0.59) | KMT2ARECQL | |
| SCHEMBL23316624 | 0.85 | PRSS1 (0.59) | — | |
| SCHEMBL13501302 | 0.83 | NR1H4 (0.76) | NR1H4MEP1BRAB9ANPC1MITF | |
| SCHEMBL3530258 | 0.83 | KMT2A (0.64) | NR1H4MEP1BFOLH1RAB9ANPC1 | |
| SCHEMBL27824222 | 0.82 | MEP1B (0.59) | NR1H4MEP1BFOLH1MAPK1KMT2A | |
| SCHEMBL24782509 | 0.82 | SLC7A5 (0.57) | NR1H4KMT2AMRGPRX4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265445-B1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-05-05 | — | — | EP | disclosed |