Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23542247 | 1.00 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542224 | 1.00 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542204 | 0.92 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23316861 | 0.92 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542230 | 0.92 | RAB9A (0.52) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542217 | 0.89 | HPGD (0.47) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542244 | 0.88 | NPC1 (0.58) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL20473377 | 0.88 | NPC1 (0.58) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542220 | 0.88 | NPC1 (0.58) | RAB9ANPC1ALDH1A1KDM4EGLA | |
| SCHEMBL23542243 | 0.88 | NPC1 (0.47) | RAB9ANPC1ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040990-B2 | Compounds containing Si atoms for optically active devices | MERCK PATENT GMBH (DE) | 2021-06-22 | — | — | US | disclosed |
| EP-3583100-B1 | COMPOUNDS CONTAINING SI ATOMS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040990-B2 | Compounds containing Si atoms for optically active devices | UACA, EYA3, PDE6C | RAB9A 1064/4885NPC1 2054/4885ALDH1A1 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.