SCHEMBL233170

SCHEMBL233170

[SiH3]NC(NC1CCCC1)(NC1CCCC1)NC1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234648 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10ADH1BADH1CADH1A
SCHEMBL11522538 0.72 ALDH1A1 (0.43) ALDH1A1HSD17B10ADH1BADH1CADH1A
SCHEMBL236481 0.72 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL234204 0.72 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL232909 0.70 ALDH1A1 (0.36) ALDH1A1HSD17B10ADH1BADH1CADH1A
SCHEMBL236416 0.70 ALDH1A1 (0.36) ALDH1A1HSD17B10ADH1BADH1CADH1A
SCHEMBL1222189 0.69 ALDH1A1 (0.45) ALDH1A1HSD17B10ADH1BADH1CADH1A
SCHEMBL236315 0.67 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL234535 0.67 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL17822027 0.67 ALDH1A1 (0.36) ALDH1A1HSD17B10ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed