SCHEMBL236481

SCHEMBL236481

CC(C)(NC1CCCC1)C(N[SiH3])(NC1CCCC1)NC1CCCC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236416 0.98 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL234204 0.86 ALDH1A1 (0.32) ALDH1A1HSD17B10EPHX1
SCHEMBL232909 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL12543733 0.77 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL12359953 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1
SCHEMBL233170 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10
SCHEMBL17822027 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL16544829 0.72 ADH1B (0.31) ALDH1A1HSD17B10
SCHEMBL17046129 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL7778181 0.71 ALDH1A1 (0.40) ALDH1A1HSD17B10EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed