SCHEMBL236315

SCHEMBL236315

[SiH3]NCCC(NC1CCCCC1)(NC1CCCCC1)NC1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EPHX1 P07099 1/20 0.31
RAD52 P43351 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233112 0.88 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL234478 0.86 MEN1 (0.30)
SCHEMBL233395 0.78 ALDH1A1 (0.36) ALDH1A1HSD17B10EPHX1
SCHEMBL234535 0.76 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL236234 0.73 ALDH1A1 (0.39) ALDH1A1HSD17B10EPHX1
SCHEMBL231546 0.70 ALDH1A1 (0.35) ALDH1A1HSD17B10
SCHEMBL234648 0.70 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1
SCHEMBL233394 0.69 KDM4E (0.36) ALDH1A1HSD17B10RAD52
SCHEMBL233170 0.67 ALDH1A1 (0.36) ALDH1A1HSD17B10
SCHEMBL234534 0.67 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed