Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316907 | 0.82 | MCL1 (0.34) | — | |
| SCHEMBL19841461 | 0.82 | MCL1 (0.34) | — | |
| SCHEMBL3749558 | 0.75 | TDP1 (0.41) | KDM4E | |
| SCHEMBL23587946 | 0.75 | CTSD (0.35) | KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL23316914 | 0.75 | HTR7 (0.31) | — | |
| SCHEMBL23316908 | 0.74 | MCL1 (0.39) | CA1CA2 | |
| SCHEMBL19841408 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5872402 | 0.72 | TDP1 (0.39) | KDM4E | |
| SCHEMBL29137898 | 0.72 | TDP1 (0.39) | KDM4E | |
| SCHEMBL25933209 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052134-B1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME (US) | 2021-05-05 | — | — | EP | disclosed |