Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23305013 | 0.88 | OGA (0.60) | OGA | |
| SCHEMBL29914326 | 0.88 | OGA (0.60) | OGA | |
| SCHEMBL23305079 | 0.82 | OGA (0.55) | OGA | |
| SCHEMBL29914314 | 0.82 | OGA (0.55) | OGA | |
| SCHEMBL23317492 | 0.82 | LMNA (0.38) | SIGMAR1OGA | |
| SCHEMBL23317416 | 0.82 | SMN1; SMN2 (0.36) | OGA | |
| SCHEMBL23317306 | 0.80 | LMNA (0.39) | SIGMAR1OPRM1KCNH2OPRK1OGA | |
| SCHEMBL23304848 | 0.77 | OGA (0.53) | OGA | |
| SCHEMBL23317493 | 0.76 | SIGMAR1 (0.41) | SIGMAR1OGA | |
| SCHEMBL23317427 | 0.75 | SIGMAR1 (0.38) | SIGMAR1OPRM1KCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086966-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |