Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23304888 | 0.89 | OGA (0.40) | — | |
| SCHEMBL23317296 | 0.83 | OGA (0.39) | CHRNB2CHRNA7CHRNA4HTR3A | |
| SCHEMBL23317227 | 0.81 | — | — | |
| SCHEMBL23317423 | 0.76 | AVPR1A (0.34) | OPRM1KCNH2 | |
| SCHEMBL23317323 | 0.74 | OGA (0.40) | — | |
| SCHEMBL23305438 | 0.73 | OGA (0.55) | — | |
| SCHEMBL23304827 | 0.71 | OGA (0.41) | — | |
| SCHEMBL23317427 | 0.71 | SIGMAR1 (0.38) | OPRM1KCNH2SIGMAR1 | |
| SCHEMBL23304805 | 0.71 | OGA (0.40) | — | |
| SCHEMBL23317197 | 0.69 | SIGMAR1 (0.44) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086966-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |