Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.56 |
| ▸ | TUBB | P07437 | 5/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69858 | 0.80 | TUBB4A (0.79) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL29398303 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL109505 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL347472 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL27741309 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL29405348 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL27183234 | 0.78 | GAA (0.54) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL20821109 | 0.78 | TRPA1 (0.58) | CYP1A2CYP3A4TSHRNFKB1ALOX15 | |
| SCHEMBL13461916 | 0.78 | KMT2A (0.53) | CYP1A2CYP3A4MEN1LMNAKMT2A | |
| SCHEMBL13461856 | 0.78 | NPC1 (0.55) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078233-B2 | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20210128667-A1 | IMMUNOPROTEASOME INHIBITORS AND IMMUNOSUPPRESSIVE AGENT IN THE TREATMENT OF AUTOIMMUNE DISORDERS | KEZAR LIFE SCIENCES | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078233-B2 | Tripeptide epoxy ketone protease inhibitors | PREP, CTRL, ENPEP | CYP1A2 1156/4885CYP3A4 570/4885TSHR 4110/4885 |
| US-20210128667-A1 | IMMUNOPROTEASOME INHIBITORS AND IMMUNOSUPPRESSIVE AGENT IN THE TREATMENT OF AUTOIMMUNE DISORDERS | PSMB6, SERPINA3, PSMB10 | CYP1A2 4144/4885CYP3A4 4340/4885TSHR 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.