Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25471916 | 0.80 | TACR1 (0.61) | TACR1MAPTPOLBLMNATP53 | |
| SCHEMBL8409365 | 0.78 | TACR1 (0.58) | TACR1MAPTPOLBLMNATP53 | |
| SCHEMBL13588694 | 0.77 | TACR1 (0.48) | TACR1MAPTEGFRLMNAMEN1 | |
| SCHEMBL13588693 | 0.76 | TACR1 (0.52) | TACR1MAPTEGFRTP53ALDH1A1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468858 | 0.73 | TACR1 (0.58) | TACR1KMT2ANPSR1BACE1LNPEP | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468756 | 0.73 | TACR1 (0.58) | TACR1KMT2ANPSR1BACE1LNPEP | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 | 0.73 | TACR1 (0.58) | TACR1KMT2ANPSR1BACE1LNPEP | |
| SCHEMBL6224832 | 0.72 | TACR1 (0.53) | TACR1MAPTPOLBTP53ALDH1A1 | |
| SCHEMBL3282594 | 0.72 | TACR1 (0.53) | TACR1MAPTPOLBTP53ALDH1A1 | |
| SCHEMBL6534778 | 0.72 | TACR1 (0.48) | TACR1EGFRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083459-A1 | PROCESS FOR THE SYNTHESIS OF DOPA COMPRISING A PHOTOLABILE PROTECTIVE GROUP, AND INTERMEDIATES FOR THE PREPARATION THEREOF | CHIRACON GMBH (DE) | 2021-05-06 | — | — | WO | disclosed |