SCHEMBL23317849

SCHEMBL23317849

Nc1ccccc1COc1cc(C=O)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.56
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
HPGD P15428 3/20 0.49
TRIM24 O15164 1/20 0.49
ALDH5A1 P51649 1/20 0.49
ABAT P80404 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
SIRT1 Q96EB6 1/20 0.40
AOX1 Q06278 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TOP2A P11388 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031969 0.80 ALDH1A1 (0.62) ALDH1A1RAB9ASMN1; SMN2HPGDTRIM24
SCHEMBL29927015 0.80 ALDH1A1 (0.62) ALDH1A1RAB9ASMN1; SMN2HPGDTRIM24
SCHEMBL21973127 0.77 ALDH1A1 (0.60) ALDH1A1RAB9ASMN1; SMN2NPC1MAPT
SCHEMBL5595040 0.77 GAA (0.52) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
Ethyl Vanillin SCHEMBL22572816 0.74 ALDH1A1 (0.82) ALDH1A1RAB9ANPC1MAPTHPGD
SCHEMBL23317779 0.74 MEN1 (0.46) ALDH1A1RAB9AMAPTKDM4EMEN1
SCHEMBL17782945 0.74 ALDH1A1 (0.72) ALDH1A1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL19782689 0.73 ALDH1A1 (0.66) ALDH1A1RAB9ASMN1; SMN2NPC1MAPT
Ethyl Vanillin SCHEMBL9808349 0.73 ALDH1A1 (0.64) ALDH1A1RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL3684285 0.72 ALDH1A1 (0.70) ALDH1A1RAB9ASMN1; SMN2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021083459-A1 PROCESS FOR THE SYNTHESIS OF DOPA COMPRISING A PHOTOLABILE PROTECTIVE GROUP, AND INTERMEDIATES FOR THE PREPARATION THEREOF CHIRACON GMBH (DE) 2021-05-06 WO disclosed