Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927015 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SIRT1MAOAMAOBTRIM24 | |
| SCHEMBL1180820 | 0.88 | MAOA (0.56) | ALDH1A1SIRT1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL3923850 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SIRT1MAOAMAOBTRIM24 | |
| SCHEMBL584489 | 0.85 | TACR2 (0.62) | ALDH1A1MAOAMAOBHPGDSMN1; SMN2 | |
| SCHEMBL29446267 | 0.85 | TACR2 (0.62) | ALDH1A1MAOAMAOBHPGDSMN1; SMN2 | |
| Ethyl Vanillin SCHEMBL28162512 | 0.85 | ALDH1A1 (0.72) | ALDH1A1SIRT1TRIM24HPGDALDH5A1 | |
| SCHEMBL2557728 | 0.85 | TACR2 (0.67) | ALDH1A1SIRT1MAOAMAOBTRIM24 | |
| SCHEMBL9811349 | 0.84 | MAOA (0.52) | ALDH1A1SIRT1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL6452430 | 0.83 | KDR (0.48) | ALDH1A1SIRT1MAOAMAOBCA12 | |
| SCHEMBL14686072 | 0.82 | KDM4E (0.70) | ALDH1A1HPGDTDP1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539642-A | Method for preparing 3,4,5-trimethoxy-3'-hydroxy-4'-alkoxy diphenylethane | SHANGHAI INST TECHNOLOGY | 2014-01-29 | — | — | CN | claimed |
| EP-3828163-B1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | AUTOTAC INC (KR) | 2026-05-20 | — | — | EP | disclosed |
| EP-4633738-A1 | CYTOTOXIC COMPOUNDS | Pheon Therapeutics Ltd (GB) | 2025-10-22 | — | — | EP | disclosed |
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | AUTOTAC INC. (KR) | 2025-09-30 | — | — | US | disclosed |
| CN-120698867-A | Preparation method of 4-ethoxy-3-hydroxybenzaldehyde | 枣阳市福星化工有限公司 | 2025-09-26 | — | — | CN | disclosed |
| CN-118878502-B | 4H-benzo [ B ] pyran derivative B86, preparation method and application thereof in resisting ricefield eel rhabdovirus | 中国水产科学研究院长江水产研究所 | 2025-04-29 | — | — | CN | disclosed |
| EP-4458916-A1 | PHOTOCATALYTICALLY ACTIVE COATING COMPOSITION, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | TriOptoTec GmbH (DE) | 2024-11-06 | — | — | EP | disclosed |
| CN-118878502-A | 4H-benzo [ B ] pyran derivative B86, preparation method and application thereof in resisting ricefield eel rhabdovirus | 中国水产科学研究院长江水产研究所 | 2024-11-01 | — | — | CN | disclosed |
| US-12024521-B2 | Isoquinoline derivatives, methods of synthesis and uses thereof | PROSETTA BIOSCIENCES, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| CN-111494395-B | Carbidopa and levodopa prodrugs and their use for treating parkinson's disease | 艾伯维公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2002022612-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |
| WO-2002004412-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| EP-1121338-A1 | METHOD FOR SYNTHESIZING DIARYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, INCLUDING TETRAHYDROFURANS | Millennium Pharmaceuticals, Inc. (US) | 2001-08-08 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000023409-A1 | METHOD FOR SYNTHESIZING DIARYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, INCLUDING TETRAHYDROFURANS | LEUKOSITE, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | disclosed |
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |
| EP-0167204-A1 | Method for improving the absorption and effectiveness of a catecholamine compound | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1986-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024521-B2 | Isoquinoline derivatives, methods of synthesis and uses thereof | POLRMT, MAVS, SYNCRIP | ALDH1A1 3238/4885SIRT1 1120/4885MAOA 1165/4885 |
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | SQSTM1, ATG7, BECN1 | ALDH1A1 4677/4885SIRT1 276/4885MAOA 4624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.