Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23300539 | 1.00 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL28572943 | 1.00 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL28584586 | 1.00 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Hydrochloric Acid SCHEMBL28598338 | 0.99 | CYP3A4 (0.76) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Hydrochloric Acid SCHEMBL28598337 | 0.99 | CYP3A4 (0.76) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL11286788 | 0.86 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL29379593 | 0.86 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL19059 | 0.86 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL23300597 | 0.85 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL23300596 | 0.85 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388952-A1 | EXPECTORANT COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | HC Synthetic Pharmaceutical Co., Ltd. (CN) | 2022-12-08 | — | — | US | disclosed |
| EP-4053103-A1 | EXPECTORANT COMPOUND AND PREPARATION METHOD AND USE THEREOF | HC Synthetic Pharmaceutical Co., Ltd. (CN) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021082501-A1 | EXPECTORANT COMPOUND AND PREPARATION METHOD AND USE THEREOF | 华创合成制药股份有限公司 | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388952-A1 | EXPECTORANT COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | SLC10A2, UGT1A6, UGT1A1 | CYP2D6 146/4885SLC6A4 66/4885KCNH2 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.