Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.97 |
| ▸ | HTT | P42858 | 1/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromhexine SCHEMBL29379593 | 1.00 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL10704011 | 0.99 | LMNA (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL18548828 | 0.99 | CYP2D6 (0.97) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL99613 | 0.99 | LMNA (1.00) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL5968149 | 0.90 | CYP2D6 (0.81) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| Bromhexine SCHEMBL8573766 | 0.90 | CYP2D6 (0.81) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL13907693 | 0.88 | CYP2D6 (0.79) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL11617745 | 0.87 | CYP2D6 (0.77) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL11622934 | 0.87 | CYP2D6 (0.77) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 | |
| SCHEMBL23318472 | 0.86 | CYP2D6 (0.75) | CYP2D6SLC6A4KCNH2ABCB11ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139860-A1 | PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS | CENTRE FOR DIGESTIVE DISEASES (AU) | 2026-05-21 | — | — | US | claimed |
| CN-122055143-A | Solid compositions containing bromhexine | 第一三共健康事业株式会社 | 2026-05-15 | — | — | CN | claimed |
| US-20260125686-A1 | COMPOSITIONS AND METHODS FOR MODULATION OF CFTR | CYSTIC FIBROSIS FOUND (US) | 2026-05-07 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4736863-A1 | NOVEL MENTHOL-EUCALYPTUS OIL ANTITUSSIVE SPRAY AND USE THEREOF | Sino-Shine Biopharmaceutical Co., Ltd (CN) | 2026-05-06 | — | — | EP | claimed |
| EP-4705274-A1 | MODIFIED FORMS OF AMBROXOL FOR THERAPEUTIC USE | Zywie LLC (US) | 2026-03-11 | — | — | EP | claimed |
| US-12539282-B2 | Bromhexine for the treatment of pain | KERN KAI UWE (DE) | 2026-02-03 | — | — | US | claimed |
| EP-4680248-A1 | PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM | Topelia Aust Limited (ACN 652 771 670) (AU) | 2026-01-21 | — | — | EP | claimed |
| US-20250332088-A1 | SUSTAINED RELEASE COMPOSITIONS | RUBICON RES PRIVATE LIMITED (IN) | 2025-10-30 | — | — | US | claimed |
| US-20250268841-A1 | Trans-Epithelial Membrane Drug Delivery System | Masiz, John J. (US) | 2025-08-28 | — | — | US | claimed |
| US-4705803-A | Method of improving resorption of injected antibacterially active substances or combinations | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1987-11-10 | — | — | US | claimed |
| EP-0088943-B1 | COMPOSITION FOR THE RESORPTION OF INJECTED ANTIBACTERIAL SUBSTANCES AND MIXTURES CONTAINING A BENZYL AMINE DERIVATIVE | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-08-13 | — | — | EP | claimed |
| EP-0069527-B1 | CYSTINE DERIVATIVES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0138020-A2 | Anti-adhesive prophylactica and medicines containing a secretolytically active benzylamine derivative | Dr. Karl Thomae GmbH (DE) | 1985-04-24 | — | — | EP | claimed |
| EP-0069259-B1 | PROLONGED-ACTION FORM OF BROMOHEXINE, AND PROCESS FOR ITS PREPARATION | Dr. Karl Thomae GmbH (DE) | 1985-01-09 | — | — | EP | claimed |
| US-4438091-A | FOR RESPIRATORY DISORDERS | DR. KARL THOMAE GMBH (DE) | 1984-03-20 | — | — | US | claimed |
| EP-0088943-A2 | Composition for the resorption of injected antibacterial substances and mixtures containing a benzyl amine derivative | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1983-09-21 | — | — | EP | claimed |
| EP-0069527-A2 | Cystine derivatives | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-01-12 | — | — | EP | claimed |
| US-4229477-A | BY NORMALIZING THE METABOLISM OF GLYCOPROTEINS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-10-21 | — | — | US | claimed |
| EP-0005733-A1 | Pharmaceutical compositions for use in the treatment of diabetic nephropathy and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1979-12-12 | — | — | EP | claimed |