Bromhexine

Bromhexine

SCHEMBL29379593

CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 5/20 1.00
▸ SLC6A4 P31645 2/20 1.00
▸ KCNH2 Q12809 2/20 1.00
▸ ABCB11 O95342 1/20 1.00
▸ ADORA3 P0DMS8 1/20 1.00
▸ AR P10275 1/20 1.00
▸ SLC6A2 P23975 1/20 1.00
▸ PDE4A P27815 1/20 1.00
▸ SLC6A3 Q01959 1/20 1.00
▸ SIGMAR1 Q99720 1/20 1.00
▸ LMNA P02545 3/20 0.97
▸ CYP3A4 P08684 2/20 0.97
▸ HTT P42858 1/20 0.97
▸ CYP1A2 P05177 3/20 0.50
▸ HIF1A Q16665 2/20 0.50
▸ CYP2C19 P33261 2/20 0.50
▸ HRH3 Q9Y5N1 2/20 0.43
▸ HRH4 Q9H3N8 1/20 0.43
▸ ALDH1A1 P00352 4/20 0.42
▸ GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromhexine SCHEMBL19059 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2ABCB11ADORA3
Bromhexine SCHEMBL10704011 0.99 LMNA (1.00) CYP2D6SLC6A4KCNH2ABCB11ADORA3
Bromhexine SCHEMBL18548828 0.99 CYP2D6 (0.97) CYP2D6SLC6A4KCNH2ABCB11ADORA3
Bromhexine SCHEMBL99613 0.99 LMNA (1.00) CYP2D6SLC6A4KCNH2ABCB11ADORA3
Bromhexine SCHEMBL5968149 0.90 CYP2D6 (0.81) CYP2D6SLC6A4KCNH2ABCB11ADORA3
Bromhexine SCHEMBL8573766 0.90 CYP2D6 (0.81) CYP2D6SLC6A4KCNH2ABCB11ADORA3
SCHEMBL13907693 0.88 CYP2D6 (0.79) CYP2D6SLC6A4KCNH2ABCB11ADORA3
SCHEMBL11617745 0.87 CYP2D6 (0.77) CYP2D6SLC6A4KCNH2ABCB11ADORA3
SCHEMBL11622934 0.87 CYP2D6 (0.77) CYP2D6SLC6A4KCNH2ABCB11ADORA3
SCHEMBL23318472 0.86 CYP2D6 (0.75) CYP2D6SLC6A4KCNH2ABCB11ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 — — EP claimed
EP-3793520-B1 AN ORAL TABLET FOR DELIVERY OF ACTIVE INGREDIENTS TO THE THROAT COMPRISING NON-DIRECTLY COMPRESSIBLE SUGAR ALCOHOL PARTICLES FERTIN PHARMA AS (DK) 2025-04-30 — — EP claimed
EP-3793518-B1 AN ORAL TABLET FOR TASTE MASKING OF ACTIVE INGREDIENTS COMPRISING NON-DIRECTLY COMPRESSIBLE SUGAR ALCOHOL PARTICLES FERTIN PHARMA AS (DK) 2025-03-26 — — EP claimed
EP-4088716-B1 AN ORAL TABLET FOR INDUCED SALIVA GENERATION FERTIN PHARMA AS (DK) 2024-10-16 — — EP claimed
EP-4308103-A1 ANTIVIRAL COMPOSITIONS AND METHODS AI Therapeutics, Inc. (US) 2024-01-24 — — EP claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 — — EP claimed
EP-3638223-B1 BROMHEXINE FOR THE TREATMENT OF PAIN KERN KAI UWE (DE) 2023-10-25 — — EP claimed
WO-2022197667-A1 ANTIVIRAL COMPOSITIONS AND METHODS YOUNG PETER R (US) 2022-09-22 — — WO claimed
EP-3003285-B1 SOLID PHARMACEUTICAL DOSAGE FORM FOR RELEASE OF AT LEAST TWO ACTIVE PHARMACEUTICAL INGREDIENTS IN THE ORAL CAVITY MCNEIL AB (SE) 2022-02-16 — — EP claimed
US-20260144746-A1 Protein Based Soft Chew Tablets FERTIN PHARMA A/S (DK) 2026-05-28 — — US disclosed
US-20260144745-A1 Sugar Free Soft Chew Tablets FERTIN PHARMA A/S (DK) 2026-05-28 — — US disclosed
EP-4734952-A1 ORAL TABLET WITH IMPROVED UNIFORMITY OF CONTENT OF ACTIVES Fertin Pharma A/S (DK) 2026-05-06 — — EP disclosed
EP-3932389-B1 COMPOSITION FOR THE TREATMENT AND PREVENTION OF AT LEAST ONE SYMPTOM OF A SECONDARY DISEASE ASSOCIATED WITH COVID-19 IN HUMANS SCHMIDT WERNER (DE) 2026-04-08 — — EP disclosed
US-12551439-B2 Flowpack for oral delivery of active ingredients FERTIN PHARMA A/S (DK) 2026-02-17 — — US disclosed
US-11351162-B2 Oral delivery vehicle containing flavoring agents FERTIN PHARMA A/S (DK) 2022-06-07 — — US disclosed
WO-2022092284-A1 COMPOSITION CONTAINING LIPID PEPTIDE AND SUCROSE ESTER 日産化学株式会社 2022-05-05 — — WO disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 — — CN disclosed
US-11260030-B2 Oral tablet for delivery of active ingredients to the gastrointestinal tract FERTIN PHARMA A/S (DK) 2022-03-01 — — US disclosed
EP-3003285-B1 SOLID PHARMACEUTICAL DOSAGE FORM FOR RELEASE OF AT LEAST TWO ACTIVE PHARMACEUTICAL INGREDIENTS IN THE ORAL CAVITY MCNEIL AB (SE) 2022-02-16 — — EP disclosed
EP-3947434-A2 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-02-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144745-A1 Sugar Free Soft Chew Tablets SI, TREH, SLC2A3 CYP2D6 954/4885SLC6A4 304/4885KCNH2 1243/4885
US-12551439-B2 Flowpack for oral delivery of active ingredients GCK, SLC2A8, SLC2A1 CYP2D6 959/4885SLC6A4 332/4885KCNH2 4233/4885
US-20260144746-A1 Protein Based Soft Chew Tablets CARHSP1, HIRA, HEATR6 CYP2D6 4072/4885SLC6A4 2003/4885KCNH2 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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