Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465308 | 0.87 | MAPT (0.43) | HAO1KDM4EHPGDALPLMAPT | |
| SCHEMBL25463661 | 0.86 | MAPT (0.45) | HAO1KDM4EHPGDL3MBTL1ALPL | |
| SCHEMBL23319888 | 0.86 | SMN1; SMN2 (0.43) | HAO1KDM4EL3MBTL1ALPLMAPT | |
| SCHEMBL29968505 | 0.84 | HAO1 (0.44) | HAO1L3MBTL1ALDH1A1SCN9ASCN4A | |
| SCHEMBL23319896 | 0.84 | HAO1 (0.52) | HAO1ALPLSCN4A | |
| SCHEMBL25464912 | 0.83 | RAB9A (0.47) | KDM4EHPGDALPLMAPTKMT2A | |
| SCHEMBL25463689 | 0.83 | SMN1; SMN2 (0.46) | KDM4EHPGDALPLMAPTALDH1A1 | |
| SCHEMBL23319972 | 0.82 | HAO1 (0.51) | HAO1ALPL | |
| SCHEMBL25464904 | 0.82 | NPC1 (0.39) | HAO1KDM4EALPLMAPTCYP1A2 | |
| SCHEMBL25464166 | 0.81 | ALPL (0.36) | HAO1KDM4EALPLMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112399873-B | Triazole glycolate oxidase inhibitors | 坎特罗治疗有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-3817816-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | Orfan Biotech Inc. (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112399873-A | Triazole glycolate oxidase inhibitor | 奥凡生物科技公司 | 2021-02-23 | — | — | CN | disclosed |