SCHEMBL25464166

SCHEMBL25464166

COC(=O)c1nn[nH]c1Oc1ccc(-c2ccc(OC(C)F)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALPL P05186 3/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ ACACB O00763 2/20 0.36
▸ ACACA Q13085 2/20 0.36
▸ BCL2 P10415 1/20 0.35
▸ MDM2 Q00987 1/20 0.35
▸ MCL1 Q07820 1/20 0.35
▸ FPR2 P25090 2/20 0.35
▸ SCN9A Q15858 2/20 0.35
▸ XDH P47989 1/20 0.34
▸ PKM P14618 2/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464912 0.84 RAB9A (0.47) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL25463689 0.84 SMN1; SMN2 (0.46) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL25464904 0.83 NPC1 (0.39) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL23319953 0.81 HAO1 (0.43) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL25463638 0.80 DRD1 (0.44) ALPLRAB9AXDHGAACYP2C9
SCHEMBL23319988 0.80 ROCK2 (0.44) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL25465308 0.79 MAPT (0.43) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL23319888 0.78 SMN1; SMN2 (0.43) ALPLNPC1RAB9ALMNAMAPT
SCHEMBL25463661 0.78 MAPT (0.45) ALPLLMNAMAPTSMN1; SMN2PKM
SCHEMBL24154823 0.78 DRD1 (0.43) LMNAMAPTKDM4EPRKAG1PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO ALPL 652/4885NPC1 2715/4885RAB9A 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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