SCHEMBL23319982

SCHEMBL23319982

CN(C)c1cccc(Oc2[nH]nnc2C(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
BCHE P06276 2/20 0.43
ACHE P22303 1/20 0.43
HAO1 Q9UJM8 10/20 0.40
CHEK2 O96017 1/20 0.39
FFAR1 O14842 1/20 0.38
APP P05067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21296882 0.80 HAO1 (0.44) HAO1
SCHEMBL21296859 0.80 HAO1 (0.44) HAO1FFAR1
SCHEMBL29799085 0.80 HAO1 (0.44) HAO1FFAR1
SCHEMBL23319939 0.80 HAO1 (0.41) HAO1
SCHEMBL21296931 0.80 PTGS1 (0.45) HAO1
SCHEMBL29799243 0.80 PTGS1 (0.45) HAO1
SCHEMBL21296942 0.80 ALDH1A1 (0.43) HAO1
SCHEMBL29799129 0.80 ALDH1A1 (0.43) HAO1
SCHEMBL25465054 0.78 APP (0.39) F2F10BCHEACHECHEK2
SCHEMBL21296947 0.78 UNG (0.42) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed
US-20210403439-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS VENTHERA, INC. 2021-12-30 US disclosed
EP-3817816-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS Orfan Biotech Inc. (US) 2021-05-12 EP disclosed
CN-112399873-A Triazole glycolate oxidase inhibitor 奥凡生物科技公司 2021-02-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO F2 2020/4885F10 2157/4885BCHE 1957/4885
US-20210403439-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO F2 2020/4885F10 2157/4885BCHE 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.