Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320352 | 0.81 | NAMPT (0.42) | ADORA3ADORA2AADORA1BRAFMAPK14 | |
| SCHEMBL23320379 | 0.79 | NAMPT (0.41) | ADORA3ADORA2AADORA1BRAFMAPK14 | |
| SCHEMBL23320568 | 0.78 | SCN9A (0.33) | ADORA3ADORA1MAPK1NAMPT | |
| SCHEMBL23320412 | 0.73 | MEN1 (0.39) | ADORA3NPC1MEN1RAB9AKMT2A | |
| SCHEMBL23320420 | 0.70 | ADORA1 (0.54) | ADORA3ADORA2AADORA1BRAFMAPK14 | |
| SCHEMBL23320489 | 0.69 | CHEK1 (0.37) | ROCK2ROCK1PRKG1CHEK1PRKACA | |
| SCHEMBL24042588 | 0.68 | NAMPT (0.77) | RAB9AROCK2NAMPTLMNAROCK1 | |
| SCHEMBL23320443 | 0.67 | ADORA1 (0.48) | ADORA3ADORA2AADORA1BRAFMAPK14 | |
| SCHEMBL30943227 | 0.67 | ADORA1 (0.48) | ADORA3ADORA2AADORA1BRAFMAPK14 | |
| SCHEMBL29472984 | 0.67 | ADORA1 (0.59) | ADORA3ADORA2AADORA1BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |