Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320352 | 0.91 | NAMPT (0.42) | NAMPTMKNK1MKNK2ADORA1ADORA2A | |
| SCHEMBL23320566 | 0.79 | NAMPT (0.35) | NAMPTADORA1ADORA2AADORA3MEN1 | |
| SCHEMBL23320378 | 0.79 | ADORA3 (0.37) | NAMPTMKNK1ADORA1ADORA2AADORA3 | |
| SCHEMBL24042588 | 0.73 | NAMPT (0.77) | NAMPTROCK2ROCK1RAB9ALMNA | |
| SCHEMBL23320410 | 0.72 | NAMPT (0.39) | NAMPTADORA3MEN1KMT2ARAB9A | |
| SCHEMBL23320396 | 0.70 | NAMPT (0.36) | NAMPTADORA1ADORA2AADORA3MAPK14 | |
| SCHEMBL23320485 | 0.70 | CHEK1 (0.37) | SLC2A1ROCK2ROCK1SLC2A4HSD17B10 | |
| SCHEMBL23320443 | 0.69 | ADORA1 (0.48) | ADORA1ADORA2AADORA3BRAFMAPK14 | |
| SCHEMBL23320420 | 0.69 | ADORA1 (0.54) | ADORA1ADORA2AADORA3BRAFMAPK14 | |
| SCHEMBL30943227 | 0.69 | ADORA1 (0.48) | ADORA1ADORA2AADORA3BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |