Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GCG | P01275 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320396 | 0.83 | NAMPT (0.36) | SCN9ANAMPTPOLBMAPTMAPK1 | |
| SCHEMBL23320566 | 0.82 | NAMPT (0.35) | SCN9ANAMPTKDM4EPOLBMAPT | |
| SCHEMBL23320378 | 0.78 | ADORA3 (0.37) | NAMPTMAPK1ADORA3ADORA1 | |
| SCHEMBL23320370 | 0.73 | KDM4E (0.43) | SCN9AKDM4EMAPTATMADORA3 | |
| SCHEMBL30943200 | 0.71 | NAMPT (0.67) | NAMPTHTT | |
| SCHEMBL24042559 | 0.71 | NAMPT (0.67) | NAMPTHTT | |
| SCHEMBL23320407 | 0.71 | FBP1 (0.38) | KDM4EMAPTHTTADORA3ADORA1 | |
| SCHEMBL23320491 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL23320489 | 0.69 | CHEK1 (0.37) | KDM4E | |
| SCHEMBL23320412 | 0.66 | MEN1 (0.39) | NAMPTKDM4EPKMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |