Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13080474 | 0.71 | MPO (0.56) | NR4A3MPOGAAALDH1A1MAPK1 | |
| Formamide SCHEMBL23320358 | 0.71 | NAMPT (0.52) | MAPK1MAPK14 | |
| Formamide SCHEMBL27781102 | 0.66 | GABRA1 (0.46) | ELANEGAAALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL31268518 | 0.66 | MPO (0.49) | NR4A3MPOALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL728873 | 0.65 | HPGD (0.44) | NR4A3MPOALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13360872 | 0.63 | POLB (0.49) | NR4A3ALDH1A1MAPK1POLBNPC1 | |
| SCHEMBL12338161 | 0.63 | NR4A3 (0.66) | NR4A3GAAALDH1A1MAPK1NPC1 | |
| SCHEMBL20337327 | 0.63 | PARP1 (0.55) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31268513 | 0.62 | CYP2C9 (0.44) | NR4A3MPOALDH1A1MAPK1POLB | |
| SCHEMBL4037627 | 0.62 | NR4A3 (0.59) | NR4A3GAAALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |