Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL23320517 | 0.83 | NAMPT (0.45) | NAMPTALDH1A1RAB9AGAAKMT2A | |
| SCHEMBL30895209 | 0.75 | NAMPT (0.52) | NAMPTALDH1A1RAB9AHTT | |
| Formamide SCHEMBL23320430 | 0.73 | NAMPT (0.54) | NAMPTALDH1A1RAB9AHTTGAA | |
| Formamide SCHEMBL23320358 | 0.71 | NAMPT (0.52) | NAMPTHTT | |
| SCHEMBL20379673 | 0.70 | NAMPT (0.65) | NAMPTALDH1A1RAB9AHTT | |
| SCHEMBL2056377 | 0.70 | RAB9A (0.74) | NAMPTRAB9AHTTGAAKMT2A | |
| SCHEMBL23320512 | 0.69 | NAMPT (0.74) | NAMPTALDH1A1RAB9AHTT | |
| SCHEMBL28620099 | 0.69 | NAMPT (0.73) | NAMPTALDH1A1RAB9AGAAKMT2A | |
| SCHEMBL23320444 | 0.69 | NAMPT (1.00) | NAMPTALDH1A1RAB9AGAAKMT2A | |
| SCHEMBL20379622 | 0.67 | NAMPT (0.55) | NAMPTALDH1A1RAB9AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | claimed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | claimed |
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |