Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320499 | 0.92 | NAMPT (0.47) | ROCK2ROCK1NAMPTRAB9A | |
| SCHEMBL23320502 | 0.84 | NAMPT (0.49) | ROCK2ROCK1NAMPTRAB9A | |
| SCHEMBL23320506 | 0.81 | ROCK2 (0.57) | PRMT3ROCK2ROCK1KDM4ENAMPT | |
| SCHEMBL23320539 | 0.75 | PRMT3 (0.52) | PRMT3ROCK2ROCK1KDM4ENAMPT | |
| SCHEMBL30943269 | 0.73 | NAMPT (0.54) | ROCK2ROCK1NAMPT | |
| SCHEMBL24042574 | 0.73 | NAMPT (0.54) | ROCK2ROCK1NAMPT | |
| SCHEMBL23320481 | 0.72 | NAMPT (0.57) | ROCK2ROCK1NAMPT | |
| SCHEMBL23320580 | 0.70 | NAMPT (0.59) | ROCK2ROCK1NAMPT | |
| SCHEMBL30943163 | 0.70 | NAMPT (0.59) | ROCK2ROCK1NAMPT | |
| SCHEMBL23320504 | 0.69 | NAMPT (0.54) | ROCK2ROCK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |