Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418905 | 0.84 | ALDH1A1 (0.40) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2125667 | 0.84 | KDM4E (0.41) | NTSR1MAOBMAOAALDH1A1KDM4E | |
| SCHEMBL30943176 | 0.76 | ALDH1A1 (0.40) | NTSR1MAOBMAOAALDH1A1KDM4E | |
| SCHEMBL2421377 | 0.73 | KMT2A (0.66) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL22004138 | 0.73 | ACLY (0.48) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3844342 | 0.72 | L3MBTL1 (0.71) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL22004127 | 0.72 | ACLY (0.51) | MAOBMAOAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2122716 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL2123823 | 0.71 | ALDH1A1 (0.48) | MAOBMAOAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30323658 | 0.70 | KMT2A (0.53) | ALDH1A1KDM4EHSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |