Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320492 | 0.87 | CYP19A1 (0.40) | CYP19A1GSK3BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23320476 | 0.87 | PTGES2 (0.35) | GSK3BNPY5R | |
| SCHEMBL23320493 | 0.87 | ALDH1A1 (0.38) | GSK3BNPY5RABCC1 | |
| SCHEMBL23320485 | 0.84 | CHEK1 (0.37) | CYP3A4CYP2D6CYP2C9KCNA5 | |
| SCHEMBL23320473 | 0.78 | CYP19A1 (0.41) | CYP19A1KMT2AAPPNR4A2MAPT | |
| SCHEMBL23320543 | 0.78 | PTGES2 (0.36) | KMT2AGSK3B | |
| SCHEMBL23320498 | 0.77 | KCNA5 (0.37) | CYP19A1KMT2AKCNA5MAPT | |
| SCHEMBL23320561 | 0.77 | ALDH1A1 (0.39) | MAPT | |
| SCHEMBL23320580 | 0.69 | NAMPT (0.59) | KMT2A | |
| SCHEMBL30943163 | 0.69 | NAMPT (0.59) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |