Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR39 | O43194 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320492 | 0.90 | CYP19A1 (0.40) | KCNA5CYP19A1CA12CA9NPC1 | |
| SCHEMBL23320490 | 0.81 | ALOX5 (0.38) | CYP19A1CA12CA9NPC1RAB9A | |
| SCHEMBL23320543 | 0.81 | PTGES2 (0.36) | NTRK1KMT2A | |
| SCHEMBL23320475 | 0.77 | CYP19A1 (0.40) | KCNA5CYP19A1MAPTKMT2A | |
| SCHEMBL23320561 | 0.76 | ALDH1A1 (0.39) | QPCTMAPTL3MBTL1POLB | |
| SCHEMBL24042594 | 0.72 | NAMPT (0.51) | MEN1KMT2A | |
| SCHEMBL30943149 | 0.72 | NAMPT (0.51) | MEN1KMT2A | |
| SCHEMBL23320476 | 0.72 | PTGES2 (0.35) | NTRK1 | |
| SCHEMBL23320494 | 0.70 | CA12 (0.45) | CA12CA9NPC1RAB9ATSHR | |
| SCHEMBL30943245 | 0.70 | CA12 (0.45) | CA12CA9NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | claimed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |