Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320490 | 0.88 | ALOX5 (0.38) | CYP19A1KMT2AALOX5MAPTALDH1A1 | |
| SCHEMBL23320474 | 0.87 | PTGES2 (0.36) | ALOX5 | |
| SCHEMBL23320491 | 0.86 | ALDH1A1 (0.38) | ROCK2ALDH1A1HPGD | |
| SCHEMBL23320489 | 0.83 | CHEK1 (0.37) | ROCK2ROCK1ALDH1A1 | |
| SCHEMBL23320475 | 0.78 | CYP19A1 (0.40) | CYP19A1KMT2AMAPTAPPNR4A2 | |
| SCHEMBL23320498 | 0.69 | KCNA5 (0.37) | CYP19A1KMT2AMAPT | |
| SCHEMBL23320543 | 0.68 | PTGES2 (0.36) | KMT2AALOX5FNTAFNTB | |
| SCHEMBL23320492 | 0.67 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL23320580 | 0.65 | NAMPT (0.59) | KMT2AROCK2ROCK1 | |
| SCHEMBL30943163 | 0.65 | NAMPT (0.59) | KMT2AROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |