Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833154 | 1.00 | CHRNB2 (0.68) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL15720996 | 0.95 | CHRNB2 (0.63) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL2063354 | 0.92 | CHRNB2 (0.67) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL15498199 | 0.92 | CHRNB2 (0.73) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL2374109 | 0.85 | CHRNB2 (0.70) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL4701140 | 0.85 | CHRNB2 (0.61) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL14028449 | 0.85 | CHRNB2 (0.69) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL29547480 | 0.84 | CHRNB2 (0.65) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL17905717 | 0.84 | CHRNB2 (0.68) | CHRNB2CHRNA4HPGDLMNACHRNB4 | |
| SCHEMBL8957329 | 0.84 | CHRNB2 (0.64) | CHRNB2CHRNA4HPGDLMNACHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677613-A | Process for producing synthetic intermediate of monocyclic pyridine derivative | 卫材R&D管理有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20230150980-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230150980-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-20170029367-A1 | Substituted Aromatic Sulfur Compounds and Methods of Their Use | CEPHALON INC (US) | 2017-02-02 | — | — | US | disclosed |
| US-9475766-B2 | Substituted aromatic sulfur compounds and methods of their use | CEPHALON, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20140005175-A1 | Substituted Aromatic Sulfur Compounds and Methods of Their Use | CEPHALON, INC. (US) | 2014-01-02 | — | — | US | disclosed |
| WO-2012116151-A2 | SUBSTITUTED AROMATIC SULFUR COMPOUNDS AND METHODS OF THEIR USE | CEPHALON, INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2012-08-02 | — | — | US | disclosed |
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010146236-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORP. (FI) | 2010-12-23 | — | — | WO | disclosed |
| US-7696225-B2 | (2-carboxamido)(3-Amino) thiophene compounds | OSI PHARMACEUTICALS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-7696225-B2 | (2-carboxamido)(3-Amino) thiophene compounds | OSI PHARMACEUTICALS, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| EP-1807419-B1 | (2-CARBOXAMIDO)(3-AMINO) THIOPHENE COMPOUNDS | OSI PHARM INC (US) | 2009-05-27 | — | — | EP | disclosed |
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150980-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | COL1A1, COL2A1, COL14A1 | CHRNB2 4800/4885CHRNA4 4773/4885HPGD 2406/4885 |
| US-20140005175-A1 | Substituted Aromatic Sulfur Compounds and Methods of Their Use | RB1, NRAS, TP53 | CHRNB2 4597/4885CHRNA4 4880/4885HPGD 942/4885 |
| US-20170029367-A1 | Substituted Aromatic Sulfur Compounds and Methods of Their Use | RB1, NRAS, TP53 | CHRNB2 4597/4885CHRNA4 4880/4885HPGD 942/4885 |
| US-20120196884-A1 | UREA SUBSTITUTED SULPHONAMIDE DERIVATIVES | ITGA1, ITGB1, ITGA2B | CHRNB2 2290/4885CHRNA4 1971/4885HPGD 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.