Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320423 | 0.86 | RORC (0.44) | NAMPTNR1H2NR1H3 | |
| SCHEMBL30323648 | 0.86 | RORC (0.44) | NAMPTNR1H2NR1H3 | |
| SCHEMBL30943213 | 0.82 | NAMPT (0.75) | NAMPT | |
| SCHEMBL23320417 | 0.82 | NAMPT (0.75) | NAMPT | |
| SCHEMBL23320422 | 0.79 | NR1H2 (0.37) | NAMPTSMN1; SMN2PIK3CDPIK3CGCYP2D6 | |
| SCHEMBL23320351 | 0.79 | MAPT (0.46) | SMN1; SMN2CYP2D6CYP2C9NR1H2NR1H3 | |
| SCHEMBL23320393 | 0.79 | MEN1 (0.40) | SMN1; SMN2CYP2D6CYP2C9NR1H2NR1H3 | |
| SCHEMBL2177704 | 0.73 | ALDH1A1 (0.58) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL19581840 | 0.70 | MAPT (0.48) | NAMPTSMN1; SMN2CYP2D6CYP3A4MAPT | |
| SCHEMBL3641867 | 0.68 | ALDH1A1 (0.54) | NAMPTSMN1; SMN2MAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |