Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320573 | 0.79 | NAMPT (0.48) | NR1H2NR1H3CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL30323648 | 0.76 | RORC (0.44) | NR1H2NR1H3NAMPTGPR119 | |
| SCHEMBL23320423 | 0.76 | RORC (0.44) | NR1H2NR1H3NAMPTGPR119 | |
| SCHEMBL23320393 | 0.76 | MEN1 (0.40) | NR1H2NR1H3CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL23320351 | 0.76 | MAPT (0.46) | NR1H2NR1H3CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL17802489 | 0.74 | ADORA3 (0.42) | NPC1LMNAMAPTRAB9ANAMPT | |
| SCHEMBL30943213 | 0.69 | NAMPT (0.75) | NAMPT | |
| SCHEMBL23320417 | 0.69 | NAMPT (0.75) | NAMPT | |
| SCHEMBL3213503 | 0.64 | PTGS2 (0.50) | MEN1NPC1LMNAMAPTRAB9A | |
| SCHEMBL31316873 | 0.63 | KCNH2 (0.46) | NR1H2NR1H3CYP2C9CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |