SCHEMBL2332072

SCHEMBL2332072

CCC(CC)C(=O)C(CCCCC(C)C)C(=O)OOC(=O)C(CCCCC(C)C)C(=O)C(CC)CC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.38
CA1 P00915 6/20 0.38
MAPK1 P28482 1/20 0.33
BLM P54132 1/20 0.32
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247917 0.83 LMNA (0.34) CA1BLMLMNAPTPN1
SCHEMBL248420 0.77 PTPN1 (0.37) CA1BLMLMNATDP1PTPN1
SCHEMBL28697771 0.75 CA1 (0.48) CA2CA1
SCHEMBL248079 0.73 CA2 (0.35) CA2CA1MAPK1BLMLMNA
SCHEMBL245120 0.73 CA1 (0.46) CA2CA1LMNA
SCHEMBL7219186 0.72 CA2 (0.41) CA2CA1MAPK1BLMLMNA
SCHEMBL7217664 0.70 CA2 (0.40) CA2CA1MAPK1
SCHEMBL7224597 0.70 CA2 (0.40) CA2CA1MAPK1
SCHEMBL7224184 0.70 CA2 (0.40) CA2CA1MAPK1
SCHEMBL7783557 0.70 CA2 (0.69) CA2CA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456257-B2 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL CHEMICALS INT BV (NL) 2020-04-01 EP disclosed
EP-1636272-B2 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2011-08-17 EP disclosed
US-7834110-B2 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N. V. (NL) 2010-11-16 US disclosed
EP-1456257-B1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL NV (NL) 2009-06-24 EP disclosed
US-20080221266-A1 Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time AKZO NOBEL N.V. (NL) 2008-09-11 US disclosed
EP-1636272-B1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2007-12-05 EP disclosed
US-7173095-B2 Polymerization process involving the dosing initiators AKZO NOBEL N. V. (NL) 2007-02-06 US disclosed
US-7109275-B2 Co-metering of organic initiators and protective colloids during polymerization reactions AKZO NOBEL N.V. (NL) 2006-09-19 US disclosed
EP-1495057-B1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL NV (NL) 2006-08-02 EP disclosed
US-20060122339-A1 Polymerization process involving the dosing initiators AKZO NOBEL N.V. (NL) 2006-06-08 US disclosed
EP-1636272-A1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS Akzo Nobel N.V. (NL) 2006-03-22 EP disclosed
US-20050080207-A1 Addition of organic initiators during the pressure drop In vinyl chloride monomer polymerization reactions AKZO NOBEL N.V. (NL) 2005-04-14 US disclosed
EP-1495057-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS Akzo Nobel N.V. (NL) 2005-01-12 EP disclosed
WO-2004113392-A1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL N.V. (NL) 2004-12-29 WO disclosed
EP-1456257-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION Akzo Nobel N.V. (NL) 2004-09-15 EP disclosed
EP-1375529-A1 Addition of organic initiators during a pressure drop in vinyl chloride monomer polymerization reactions Akzo Nobel N.V. (NL) 2004-01-02 EP disclosed
WO-2003087168-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-10-23 WO disclosed
US-20030199656-A1 Co-metering of organic initiators and protective colloids during polymerization reactions WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2003-10-23 US disclosed
WO-2003054039-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed