Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245120 | 0.85 | CA1 (0.46) | LMNACA1 | |
| SCHEMBL2332072 | 0.83 | CA2 (0.38) | LMNABLMPTPN1CA1 | |
| SCHEMBL248420 | 0.82 | PTPN1 (0.37) | LMNABLMPTPN1RARBKDM4C | |
| SCHEMBL6311485 | 0.71 | TDP1 (0.42) | CA1 | |
| SCHEMBL19861335 | 0.69 | TDP1 (0.49) | KDM4CKDM4APHF8KDM2A | |
| SCHEMBL247918 | 0.69 | KDM4C (0.40) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL7591821 | 0.69 | BLM (0.52) | LMNABLMKDM4CKDM4APHF8 | |
| SCHEMBL19861153 | 0.69 | BLM (0.52) | LMNABLMKDM4CKDM4APHF8 | |
| SCHEMBL7222773 | 0.68 | RARB (0.41) | LMNABLMPTPN1RARBKDM4C | |
| SCHEMBL7634837 | 0.68 | ZDHHC7 (0.39) | LMNABLMPTPN1KDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588502-B1 | POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION | NOURYON CHEMICALS INT BV (NL) | 2021-03-31 | — | — | EP | disclosed |
| EP-1456257-B2 | ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION | AKZO NOBEL CHEMICALS INT BV (NL) | 2020-04-01 | — | — | EP | disclosed |
| US-8987391-B2 | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-03-24 | — | — | US | disclosed |
| US-20130211019-A1 | Polymerization Process with In-Situ Initiator Formation | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2013-08-15 | — | — | US | disclosed |
| EP-2588502-A1 | POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION | Akzo Nobel Chemicals International B.V. (NL) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012000916-A1 | POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2012-01-05 | — | — | WO | disclosed |
| EP-1636272-B2 | POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS | AKZO NOBEL NV (NL) | 2011-08-17 | — | — | EP | disclosed |
| US-7834110-B2 | Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time | AKZO NOBEL N. V. (NL) | 2010-11-16 | — | — | US | disclosed |
| EP-1456257-B1 | ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION | AKZO NOBEL NV (NL) | 2009-06-24 | — | — | EP | disclosed |
| US-20080221266-A1 | Polymerization in presence of promoters and surfactant; overall polymerization time is reduced by a reduction of the pressure drop time | AKZO NOBEL N.V. (NL) | 2008-09-11 | — | — | US | disclosed |
| US-20060122339-A1 | Polymerization process involving the dosing initiators | AKZO NOBEL N.V. (NL) | 2006-06-08 | — | — | US | disclosed |
| EP-1636272-A1 | POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS | Akzo Nobel N.V. (NL) | 2006-03-22 | — | — | EP | disclosed |
| US-20050080207-A1 | Addition of organic initiators during the pressure drop In vinyl chloride monomer polymerization reactions | AKZO NOBEL N.V. (NL) | 2005-04-14 | — | — | US | disclosed |
| EP-1495057-A1 | CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS | Akzo Nobel N.V. (NL) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004113392-A1 | POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS | AKZO NOBEL N.V. (NL) | 2004-12-29 | — | — | WO | disclosed |
| EP-1456257-A1 | ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION | Akzo Nobel N.V. (NL) | 2004-09-15 | — | — | EP | disclosed |
| EP-1375529-A1 | Addition of organic initiators during a pressure drop in vinyl chloride monomer polymerization reactions | Akzo Nobel N.V. (NL) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003087168-A1 | CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS | AKZO NOBEL N.V. (NL) | 2003-10-23 | — | — | WO | disclosed |
| US-20030199656-A1 | Co-metering of organic initiators and protective colloids during polymerization reactions | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2003-10-23 | — | — | US | disclosed |
| WO-2003054039-A1 | ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS | AKZO NOBEL N.V. (NL) | 2003-07-03 | — | — | WO | disclosed |