SCHEMBL2332208

SCHEMBL2332208

c1ccc(N(c2cccc3ccccc23)c2c3ccccc3c(N(c3ccccc3)c3cccc4ccccc34)c3cc4ccccc4cc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.43
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
DHFR P00374 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
PTBP1 P26599 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13250576 0.98 SIGMAR1 (0.42) SIGMAR1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13250569 0.93 SIGMAR1 (0.42) SIGMAR1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL4650694 0.93 SIGMAR1 (0.47) SIGMAR1ALDH1A1HSD17B10L3MBTL1CYP1A2
SCHEMBL13250570 0.91 SIGMAR1 (0.46) SIGMAR1ALDH1A1HSD17B10L3MBTL1CYP1A2
SCHEMBL14069734 0.91 SIGMAR1 (0.38) SIGMAR1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL4921270 0.89 SIGMAR1 (0.45) SIGMAR1ALDH1A1HSD17B10L3MBTL1CYP1A2
SCHEMBL30205806 0.88 SIGMAR1 (0.44) SIGMAR1ALDH1A1HSD17B10L3MBTL1CYP1A2
SCHEMBL981539 0.88 SIGMAR1 (0.44) SIGMAR1ALDH1A1HSD17B10L3MBTL1CYP1A2
SCHEMBL9971973 0.87 ALDH1A1 (0.37) SIGMAR1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL9971932 0.86 SIGMAR1 (0.38) SIGMAR1ALDH1A1CYP1B1L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
EP-2109898-B1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2011-08-17 EP disclosed
EP-2109898-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2009-10-21 EP disclosed
WO-2008094399-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2008-08-07 WO disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US disclosed