SCHEMBL9971973

SCHEMBL9971973

c1ccc(N(c2ccc3ccccc3c2)c2c3ccccc3cc3c(N(c4ccccc4)c4cccc5ccccc45)c4ccccc4cc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
SIGMAR1 Q99720 7/20 0.37
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP1A2 P05177 2/20 0.30
HPGD P15428 1/20 0.30
PTPN1 P18031 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14069734 0.96 SIGMAR1 (0.38) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL13304810 0.90 SIGMAR1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL12442846 0.89 CYP2A6 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL13250576 0.88 SIGMAR1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL13767879 0.88 SIGMAR1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL14867151 0.87 SIGMAR1 (0.40) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL17468436 0.87 SIGMAR1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL2332208 0.87 SIGMAR1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL2325158 0.86 SIGMAR1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1
SCHEMBL24702723 0.85 SIGMAR1 (0.42) ALDH1A1HSD17B10HIF1ACYP1B1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
EP-1775335-A2 Organic lectroluminescent element IDEMITSU KOSAN COMPANY LIMITED (JP) 2007-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885HIF1A 3576/4885
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885HIF1A 3576/4885
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE ARL1, RIF1, EML4 ALDH1A1 699/4885HSD17B10 3421/4885HIF1A 3654/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885HIF1A 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.