Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332925 | 0.76 | S1PR1 (0.32) | HTTALDH1A1MAPT | |
| SCHEMBL2360713 | 0.72 | KMT2A (0.51) | HTTALDH1A1 | |
| SCHEMBL95795 | 0.70 | — | — | |
| SCHEMBL5583613 | 0.69 | POLB (0.41) | HTTALDH1A1MAPT | |
| SCHEMBL27621465 | 0.69 | MAPT (0.34) | HTTALDH1A1MAPT | |
| SCHEMBL5583577 | 0.66 | HTR2A (0.42) | ALDH1A1MAPT | |
| SCHEMBL694049 | 0.66 | KDM4E (0.44) | HTTALDH1A1 | |
| SCHEMBL1375267 | 0.65 | MAPT (0.42) | HTTALDH1A1MAPT | |
| SCHEMBL231083 | 0.65 | DPP4 (0.43) | ALDH1A1MAPT | |
| SCHEMBL1446587 | 0.65 | ALDH1A1 (0.49) | HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099764-A2 | NOVEL PYRIMIDINE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-18 | — | — | WO | disclosed |