⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621465 | 0.98 | MAPT (0.34) | — | |
| SCHEMBL8764 | 0.82 | — | — | |
| SCHEMBL5583613 | 0.81 | POLB (0.41) | — | |
| SCHEMBL11659532 | 0.79 | HTR2A (0.43) | — | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | — | |
| SCHEMBL10780424 | 0.77 | — | — | |
| SCHEMBL596846 | 0.77 | L3MBTL1 (0.39) | — | |
| SCHEMBL1231512 | 0.77 | CSNK2A1 (0.43) | — | |
| SCHEMBL4532814 | 0.77 | L3MBTL1 (0.40) | — | |
| SCHEMBL28251730 | 0.76 | CA2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2201 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104384-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2024-05-23 | — | — | WO | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| EP-3893645-B1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2024-04-17 | — | — | EP | claimed |
| CN-117486836-A | Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound | 遵义医科大学 | 2024-02-02 | — | — | CN | claimed |
| CN-115820203-B | High-voltage insulating tape with self-luminous warning function and preparation method thereof | 中电材料科技(嘉兴)有限公司 | 2023-12-05 | — | — | CN | claimed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | claimed |
| EP-3601216-B1 | SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-25 | — | — | EP | claimed |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-05 | — | — | US | claimed |
| CN-114524751-B | Aryl nitrile compound and preparation method thereof | 海南大学 | 2023-09-05 | — | — | CN | claimed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| US-4910200-A | Agricultural fungicide | CELAMERCK GMBH & CO. KG (DE) | 1990-03-20 | — | — | US | claimed |
| EP-0325936-A2 | Aminoguanidine derivatives and inhibitory agents on maillard reaction containing them as active ingredients | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| EP-0311110-A2 | Direct positive color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-12 | — | — | EP | claimed |
| EP-0219756-A1 | Acrylic amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-29 | — | — | EP | claimed |
| EP-0066922-A1 | Process for preparing asymmetric ureas from urethans and amines | ANIC S.p.A. (IT) | 1982-12-15 | — | — | EP | claimed |
| US-4316015-A | 6H-1,2,4,6-Thiatriazine-1,1-dioxides | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4008249-A | HERBICIDE, PLANT GROWTH REGULATOR | BASF AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-3932630-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | claimed |