SCHEMBL23323289

SCHEMBL23323289

CCCCCOCC(=O)C(C)(C)OC(=O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.54
NAAA Q02083 1/20 0.36
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
EPHX1 P07099 1/20 0.34
PLA2G2C Q5R387 2/20 0.34
EPHX2 P34913 1/20 0.34
TSHR P16473 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33
USP2 O75604 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
FAAH O00519 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24378698 0.79 NAAA (0.43) NAAACYP4F2CYP4A11EPHX1TSHR
SCHEMBL15710993 0.76 CES2 (0.69) CES2NAAAEPHX2MEN1THRB
SCHEMBL23292884 0.73 ALDH1A1 (0.44) NAAACYP4F2CYP4A11EPHX1TSHR
SCHEMBL23323159 0.72
SCHEMBL10026749 0.70 CES2 (0.60) CES2TSHRMEN1KMT2AFAAH
SCHEMBL332803 0.69 NAAA (0.56) NAAAEPHX1TSHRFAAH
SCHEMBL17946938 0.69 CES2 (0.55) CES2NAAAEPHX1PLA2G2CEPHX2
SCHEMBL23292883 0.69 GRM1 (0.40) CYP4F2CYP4A11TSHR
SCHEMBL12044642 0.69 CA1 (0.40) CES2NAAAMEN1KMT2AMAPT
SCHEMBL25881773 0.69 CES2 (0.55) CES2NAAAPLA2G2CEPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816149-A1 ISOBUTYRIC ESTER COMPOUND HAVING BUTYRYLOXY GROUP OR PIVALOYLOXY GROUP AT ? POSITION, AND PERFUME COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-05 EP disclosed