Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308932 | 0.82 | — | — | |
| SCHEMBL17613261 | 0.82 | — | — | |
| Dimethylamine SCHEMBL9903434 | 0.78 | ANPEP (0.30) | ANPEP | |
| Nitric Acid SCHEMBL29270163 | 0.73 | — | — | |
| SCHEMBL295959 | 0.72 | LMNA (0.39) | — | |
| Butane SCHEMBL9318226 | 0.72 | CA5A (0.53) | CA5ACA5BALDH1A1 | |
| Nitric Acid SCHEMBL5950869 | 0.71 | — | — | |
| Nitric Acid SCHEMBL813725 | 0.71 | CA5A (0.44) | ANPEPCA5ACA5BALDH1A1 | |
| SCHEMBL237214 | 0.69 | — | — | |
| SCHEMBL309741 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137970-A1 | NITRIC OXIDE-RELEASING PARTICLES | Diabetic Health, Inc. | 2021-05-13 | — | — | US | disclosed |