Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL30555522 | 0.91 | PAOX (0.38) | CA5ACA5BPAOXTSHRADH1B | |
| Nitric Acid SCHEMBL7567345 | 0.84 | ALDH1A1 (0.50) | CA5ACA5BPAOXTSHRADH1B | |
| Dipentylamine SCHEMBL7568173 | 0.82 | ALDH1A1 (0.62) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL8193567 | 0.81 | — | — | |
| Dipentylamine SCHEMBL3469134 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL7562827 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL6390465 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL6392617 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL7562435 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 | |
| Nitric Acid SCHEMBL7567094 | 0.80 | ALDH1A1 (0.59) | PAOXTSHRADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7658872-B2 | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS, INC. (US) | 2010-02-09 | — | — | US | claimed |
| CN-100339153-C | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS INC (US) | 2007-09-26 | — | — | CN | claimed |
| CN-1646203-A | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS INC (US) | 2005-07-27 | — | — | CN | claimed |
| US-20050103705-A1 | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS, INC. | 2005-05-19 | — | — | US | claimed |
| EP-1483033-A4 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS INC (US) | 2005-04-13 | — | — | EP | claimed |
| EP-1483033-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS, INC. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003074152-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | GE OSMONICS, INC. (US) | 2003-09-12 | — | — | WO | claimed |
| US-20020016505-A1 | Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | US | claimed |
| CN-1321720-A | Storage medium of latent heat storage system | MERCK PATENT GMBH (DE) | 2001-11-14 | — | — | CN | claimed |
| EP-1148108-A1 | Storage media for latent heat storage units | MERCK PATENT GmbH (DE) | 2001-10-24 | — | — | EP | claimed |
| CN-105189531-B | Peptides for skin rejuvenation and methods of use thereof | 安特易斯有限公司 | 2020-02-21 | — | — | CN | disclosed |
| WO-2020022503-A1 | NON-COVALENT NANOCARBON-POLYMER HYBRID COMPOSITION | 国立大学法人名古屋大学 | 2020-01-30 | — | — | WO | disclosed |
| EP-2743262-B1 | Method for Obtaining a Triazine Compound with at least one Tertiary Amino Group | BOREALIS AGROLINZ MELAMINE (AT) | 2016-04-27 | — | — | EP | disclosed |
| US-9314743-B2 | Residential reverse osmosis system | PENTAIR RESIDENTIAL FILTRATION, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| CN-105189531-A | Peptides for skin rejuvenation and methods of using the same | NEOCUTIS SA | 2015-12-23 | — | — | CN | disclosed |
| CN-1329361-A | Application of phase transformation material in radiator for electronic element and device | MERCK PATENT GMBH (DE) | 2002-01-02 | — | — | CN | disclosed |
| EP-1162659-A2 | Use of PCM in heat sinks for electronic devices | MERCK PATENT GmbH (DE) | 2001-12-12 | — | — | EP | disclosed |
| CN-1321720-A | Storage medium of latent heat storage system | MERCK PATENT GMBH (DE) | 2001-11-14 | — | — | CN | disclosed |
| EP-1148108-A1 | Storage media for latent heat storage units | MERCK PATENT GmbH (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-4370402-A | Dye reducing composition for dye transfers, photographic transparencies and color prints | ANDERSON HARRY | 1983-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016505-A1 | Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling | HSPH1, HSP90AA1, HSPA1A | CA5A 3019/4885CA5B 3016/4885PAOX 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.