SCHEMBL23327869

SCHEMBL23327869

O=c1[nH]c2ncccc2c2c1sc1ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 3/20 0.61
TNKS2 Q9H2K2 3/20 0.61
AURKA O14965 3/20 0.55
PARP1 P09874 1/20 0.55
KRAS P01116 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HTT P42858 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HCRTR1 O43613 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
CDK4 P11802 2/20 0.44
CCND1 P24385 2/20 0.44
CYP1A2 P05177 1/20 0.43
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683845 1.00 TNKS (0.61) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL19988629 0.84 MEN1 (0.45) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL23353333 0.80 TNKS (0.67) TNKSTNKS2PARP1KRASMEN1
SCHEMBL16751666 0.78 GABRA1 (0.46) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL23353331 0.77 TNKS (0.71) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL23353225 0.77 TNKS (0.71) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL29865532 0.77 TNKS (0.71) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL29865534 0.77 TNKS (0.71) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL15436405 0.75 MEN1 (0.43) TNKSTNKS2AURKAPARP1KRAS
SCHEMBL6531057 0.72 PARP1 (1.00) TNKSTNKS2AURKAPARP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415949-B2 Compound, organic electroluminescent device, and display device SK INC. (KR) 2025-09-16 US disclosed
US-20210143337-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE SK MATERIALS CO., LTD. (KR) 2021-05-13 US disclosed
US-20210143337-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE SK MATERIALS CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415949-B2 Compound, organic electroluminescent device, and display device L1CAM, EML4, OCIAD2 TNKS 4515/4885TNKS2 4432/4885AURKA 2604/4885
US-20210143337-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE L1CAM, EML4, OCIAD2 TNKS 4515/4885TNKS2 4432/4885AURKA 2604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.