SCHEMBL23353333

SCHEMBL23353333

O=c1[nH]c2cccnc2c2c1sc1ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 4/20 0.67
TNKS2 Q9H2K2 4/20 0.67
PARP1 P09874 3/20 0.57
KDM4E B2RXH2 2/20 0.55
KRAS P01116 1/20 0.51
HTT P42858 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HCRTR1 O43613 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
CYP1A2 P05177 1/20 0.47
PPARG P37231 1/20 0.47
NCOA2 Q15596 1/20 0.47
NCOA1 Q15788 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
MAP3K9 P80192 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19988475 0.81 MEN1 (0.53) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL23327869 0.80 TNKS (0.61) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL31683845 0.80 TNKS (0.61) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL16751658 0.80 GABRA1 (0.51) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL24767906 0.80 GABRA1 (0.49) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL19988482 0.80 MEN1 (0.51) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL15318798 0.79 GABRA1 (0.48) TNKSTNKS2PARP1KDM4EKRAS
SCHEMBL19988607 0.77 MAP3K9 (0.55) TNKSTNKS2PARP1KRASMEN1
SCHEMBL14933613 0.75 PARP1 (0.77) TNKSTNKS2PARP1KDM4EMEN1
SCHEMBL23353331 0.75 TNKS (0.71) TNKSTNKS2PARP1KDM4EKRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210143337-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE SK MATERIALS CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210143337-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE L1CAM, EML4, OCIAD2 TNKS 4515/4885TNKS2 4432/4885PARP1 4256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.